Pittsburgh, which has won three of its past four games, scored three runs in the fifth off reliever Chris Volstad (0-2) to take the lead for good, 7-5.

Corey Dickerson was 4-for-5 with two RBIs and Starling Marte was 3-for-5 with an RBI for the Pirates.

Welington Castillo hit two homers and knocked in three runs for Chicago, which lost its fourth straight and eighth in nine games. The White Sox dropped to 3-14 at home.

Pittsburgh's Ivan Nova had his second consecutive rough start, giving up five runs and six hits in two innings, his shortest outing with the Pirates. Against Washington on May 2, he allowed 11 hits and a season-high eight runs in 4 2/3 innings.

Tyler Glasnow (1-1), the first of five Pirates relievers, gave up one hit in 2 1/3 scoreless innings. He struck out three without issuing a walk.

Chicago starter Lucas Giolito allowed four runs and seven hits in four innings.

The White Sox scored four in the first, capped by Castillo's two-run homer. Earlier, Yolmer Sanchez hit an RBI triple and scored on Jose Abreu's groundout. Nova needed 51 pitches to escape the inning.

Giolito needed the same, 51 pitches, in the second, when Pittsburgh tied it 4-4.

Jose Osuna had an RBI single, Colin Moran drove in a run on a fielder's choice, Gregory Polanco hit an RBI double, and Polanco scored on Marte's single.

Chicago regained the lead, 5-4, in the second on Abreu's RBI double.

In the Pirates' three-run fifth, Moran banged a two-run double and Jordy Mercer added an RBI single to take put Pittsburgh on top for good, 7-5.

The Pirates tacked on two more in the sixth, on Josh Bell's RBI triple and Dickerson's RBI single.

Dickerson added an RBI single in the seventh to increase the margin to 10-5.

Castillo hit his second homer of the game and fifth of the season to lead off the eighth.

--Field Level Media