TORONTO -- Marco Estrada went for a walk on the wild side Friday night and that suited the Boston Red Sox just fine as they came back to defeat the Toronto Blue Jays 7-4 in 11 innings.

After Justin Smoak staked Estrada to a first-inning lead with a three-run homer, the right-handed starter gave most of it back in 4 1/3 innings with a career-high seven walks, two hits and two runs.

"I was wild today, plain and simple," Estrada said.

Boston's Xander Bogaerts singled home the go-ahead run in the top of the 11th inning and Deven Marrero added a two-run single to give him three RBIs on the game.

Hanley Ramirez led off the 11th with a double against Aaron Loup (2-2) and took third on a single by Jackie Bradley Jr. Bogaerts, who entered the game in the 10th at shortstop, singled to right with one out to put the Red Sox (45-35) into the lead.

Glenn Sparkman replaced Loup to make his major league debut. A double steal moved runners to second and third to set up Marrero's single.

Bogaerts was supposed to have the game off but was needed late in the game.

"We were trying to do everything to give him the full day down but we had to tap into everybody," Red Sox manager John Farrell said. "He put a great swing on a pitch to push one through the right side. It took a lot of guys for this one to be finished off."

Blaine Boyer (1-1) pitched two innings in relief and Craig Kimbrel pitched a perfect bottom of the 11th to earn his 23rd save.

"It's kind of tough against (Loup) to get the ball in the air," Bogaerts said. "I didn't do anything today, no BP, nothing. The manager needed me and he put me in there. I'm happy I did my part to help us win.

"I didn't think they were going to pitch to me but they opted to do that. That's when I kind of locked it in a little more like 'OK, let's go. Let's try to get that run in.' "

Justin Smoak had a three-run homer for the Blue Jays (37-42) in the first inning. Troy Tulowitzki also homered for Toronto.

Boston starter Doug Fister allowed three runs, four hits and three walks (one intentional) in five innings.

Bradley led off the sixth with a double on a fly ball that left fielder Ezequiel Carrera lost in the twilight. After Christian Vazquez walked, the runners moved up on Tzu-Wei Lin's comebacker to the pitcher and Marrero tied the game with a single to left.

Mookie Betts flied out to shallow right center and Jeff Beliveau replaced Danny Barnes. Andrew Benintendi doubled on a grounder down the left-field line and Boston led 4-3.

Tulowitzki tied the game with his fifth homer of the season on the second pitch of the bottom of the sixth by Boston reliever Heath Hembree.

Ramirez doubled to center against Roberto Osuna with one out in the ninth, but the Blue Jays closer ended the inning on a pop out to third and a fly out to left.

Boyer pitched around a one-out single in the bottom of the ninth to send the game to extra innings. Loup survived three walks (two intentional) and a wild pitch in the top of the 10th and Boyer had a perfect bottom of the 10th.

Toronto took a 3-0 lead in the first inning on the 22nd homer of the season by Smoak.

Estrada, who had pitched around two walks in the first inning, survived walking the first three batters of the third. He retired Benintendi and Dustin Pedroia before striking out Mitch Moreland.

"I didn't have a feel for anything," Estrada said. "I had no feel for the four-seam fastball, which rarely happens and obviously everything comes off that so every pitch sucked. We had a great chance to win, the boys put up some runs early and I let it get away, I guess."

Estrada issued his seventh walk of the game to Marrero to lead off the fifth inning and Betts followed with an infield single to third, the first Boston hit of the game. Pedroia scored both runners with a double to left-center field before Barnes replaced Estrada.

"I've never seen anything like that that and I guarantee it's never happened to him," Blue Jays manager John Gibbons said. "I don't think he had a real good feel, it looks he was rushing a little bit. Something was out of whack, he didn't give up any hits that's for sure. He gave up all those walks, that's uncharacteristic for him."

NOTES: Toronto RHP Glenn Sparkman (fractured right thumb) was reinstated from the 60-day disabled list Friday and RHP Chris Smith was optioned to Triple-A Buffalo. Sparkman was taken in the Rule 5 draft from the Kansas City Royals and had been on the DL all season. ... Boston 2B Dustin Pedroia returned to the lineup Friday after taking Thursday off to tend to some nagging injuries. ... Boston LHP Chris Sale (10-3, 2.77 ERA) will oppose Toronto LHP Francisco Liriano (4-3, 5.46 ERA) Saturday afternoon in the second game of the series.